Since people keep asking me all the time:
These are the best settings, your game looks pretty and your FPS are stable. All the other settings are causing FPS instabilities, even on high end rigs, they might be minor, but as a long time CS player I want my FPS as stable as possible.
For those who have low end system:
Game rendering, Texture quality, Animate Potrait and High quality dashboard are "free" settings, they make the game way prettier but cost no performance.
Set effects and shadow on low/off, vsync off and High quality water also on off, then you have the exact same performance as on everything on low but the game actually looks pretty.
There, you have your answer, now stop annoying me.